What is your opinion about Grease Pencil animation? This was getting kicked around a few months ago, not sure what the status on it is now. I’d say that layers is probably the single biggest missing feature. One important thing is that texture painting in Blender might need to be established well firstly to be used as a foundation. I'm looking into developing some basic 2d features and I just wanted to see if there was any interest. Finally, these tools could also be used for creating animated textures for 3d animations or games which could be interesting. Blender being a 3d software, we already have a leg up there. Secondly, modern 2d animation software like Toon Boom Harmony includes basic 3d capability for things like creating parallax for 2d layers and support for 3d models of things that may be too hard to draw/animate. If done correctly, these could create a very tightly integrated 2d animation pipeline.
Namely the texture paint brushes, animation editors, compositor, and vse. First of all, Blender already has a pretty good foundation for 2d animation.
If your answer is “why the hell would we add 2d animation features to a 3d software?”, please give me a moment to defend my sanity. If your answer is yes, please comment a feature (or features) that you would consider essential to a 2d animation workflow. For clarification, this means traditional hand drawn animation using the texture paint brushes.